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A PHASE III TRIAL OF SHORT TERM ANDROGEN DEPRIVATION WITH PELVIC LYMPH NODE OR PROSTATE BED ONLY RADIOTHERAPY (SPPORT) IN PROSTATE CANCER PATIENTS WITH A RISING PSA AFTER RADICAL PROSTATECTOMY
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Disease Site:
Genitourinary
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Protocol Number:
R0534
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Status:
OPEN
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Key Eligibility:
adenocarcinoma tx'ed primarily w/radical prostatectomy; lympy negative; no prior androgen dep ttx started after prostatectomy orprior to registration
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File:
Download
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Description:
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Double-Blind, Placebo-Controlled Study of Magnesium Supplements to Reduce Menopausal Hot Flashes
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Disease Site:
Cancer Control
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Protocol Number:
N10C2
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Status:
OPEN
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Key Eligibility:
History of br cancer; bothersome hot flashes for more than 30 days; no prior us of Mg for hot flashes
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File:
Download
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Description:
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Phase I/II Study of Vorinostat (Suberoylanilide Hydroxamic Acid [SAHA]), Temozolomide, and Radiation Therapy in Patients with Newly Diagnosed Glioblastoma
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Disease Site:
Brain
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Protocol Number:
N0874
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Status:
OPEN
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Key Eligibility:
Newly diagnosed glioblastoma
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File:
Download
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Description:
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Phase III, Randomized, Study of Sulfasalazine versus Placebo in the Prevention of Acute Diarrhea in Patients Receiving Pelvic Radiation Therapy
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Disease Site:
Cancer Control
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Protocol Number:
N08C9
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Status:
OPEN
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Key Eligibility:
Subjects receiving pelvic RT; no mets beyond pelvic region, no perineal irradiation or abdominal perineal resection
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File:
Download
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Description:
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Randomized, Placebo-Controlled, Double-Blind Phase 2 Study of mFOLFOX6 Chemotherapy Plus Ramucirumab Drug Product (IMC-1121B) versus mFOLFOX6 Plus Placebo for Advanced Adenocarcinoma of the Esophagus, Gastroesophageal Junction, or Stomach
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Disease Site:
Gastrointestinal
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Protocol Number:
I4T-MC-JVBT
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Status:
OPEN
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Key Eligibility:
confirm of adenocarcinoma of esophagus, GEJ, or stomach (adenoquamous eligible); metastatic/locally advanced, unresectable
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File:
Download
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Description:
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Vaginal DHEA for Vaginal Symptoms: A Phase III Randomized, Double Blind, Placebo-
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Disease Site:
Cancer Control
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Protocol Number:
N10C1
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Status:
OPEN
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Key Eligibility:
Post-Menopausal; History of breast or gyno cancer - no current disease
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File:
Download
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Description:
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Phase I/Randomized Phase II Double Blind Study of Either Dasatinib or Placebo Combined with
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Disease Site:
Brain
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Protocol Number:
N0872
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Status:
OPEN
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Key Eligibility:
Glioblastoma multiforme (grade 4 astrocytoma)
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File:
Download
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Description:
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Vaginal DHEA for Vaginal Symptoms: A Phase III Randomized, Double Blind, Placebo-
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Disease Site:
Cancer Control
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Protocol Number:
N10C1
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Status:
OPEN
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Key Eligibility:
Post-Menopausal w/history of breast or gynecologic CA - no current disease; significant vaginal complaints
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File:
Download
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Description:
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Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer
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Disease Site:
Cancer Control
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Protocol Number:
MA32F
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Status:
OPEN
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Key Eligibility:
Consented to MA32 but not yet initiated; current or planned RT
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File:
Download
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Description:
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Randomized Phase III Trial of mFOLFOX7 or XELOX Plus Bevacizumab Versus 5-Fluorouracil/Leucovorin or Capecitabine Plus Bevacizumab as First-line Treatment in Elderly Patients with Metastatic Colorectal Cancer
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Disease Site:
Gastrointestinal
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Protocol Number:
N0949
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Status:
OPEN
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Key Eligibility:
>70 yrs
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File:
Download
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Description:
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The Oncotype DX® Colon Cancer Assay for Stage II Colon Carcinoma: Does it Impact Physician Adjuvant Treatment Decision Making and Patient Satisfaction?
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Disease Site:
Gastrointestinal
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Protocol Number:
RC0948
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Status:
OPEN
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Key Eligibility:
15 new colon pts/yr; completely resected stage II w/T3 tumors
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File:
Download
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Description:
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A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon a-2b for Resected High-risk Melanoma
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Disease Site:
Melanoma
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Protocol Number:
E1609
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Status:
OPEN
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Key Eligibility:
Completely resected disease; disease free status; no other malignancies
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File:
Download
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Description:
INVESTIGATOR TRAINING REQUIRED PRIOR TO ENROLLMENT. SEE SECTION 4.6.4 OF PROTOCOL
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A PHASE III RANDOMIZED TRIAL OF METFORMIN VERSUS PLACEBO ON RECURRENCE AND SURVIVAL IN EARLY STAGE BREAST CANCER
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Disease Site:
Breast
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Protocol Number:
MA32
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Status:
OPEN
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Key Eligibility:
Invasive breast cancer dx'ed and resected wtihin 12 months prior to randomization. No prior breast cancer.
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File:
Download
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Description:
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A Phase III Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women with Node-Positive or
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Disease Site:
Breast
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Protocol Number:
B46I
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Status:
OPEN
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Key Eligibility:
unilateral invasive adenocarcinoma, HER2-negative, no T4, no metastatic disease
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File:
Download
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Description:
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A Phase III Study Evaluating the Role of Perioperative Chemotherapy in Patients with Potentially Resectable Hepatic Colorectal Metastases
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Disease Site:
Gastrointestinal
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Protocol Number:
NSABP C11
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Status:
OPEN
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Key Eligibility:
Histologic confirmation of colorectal adenocarcinoma, no anal, small bowel, or appendiceal carcinoma or any other colorectal malignant diseases (sarcoma, lymphoma, carcinoid)
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File:
Download
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Description:
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A Randomized Phase III Trial of Adjuvant Therapy Comparing
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Disease Site:
Breast
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Protocol Number:
B47
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Status:
OPEN
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Key Eligibility:
The tumor must be unilateral invasive adenocarcinoma of the breast on histologic exam; HER2 status of the primary tumor must be evaluated prior to randomization; all testing performed must indicate that the tumor is HER2-low
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File:
Download
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Description:
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A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer
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Disease Site:
Breast
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Protocol Number:
E2108
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Status:
OPEN
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Key Eligibility:
Patients (male or female) must have an intact primary (not recurrent) invasive
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File:
Download
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Description:
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A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER-2 Negative Breast Cancer with Recurrence Score (RS) of 25 or Less
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Disease Site:
Breast
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Protocol Number:
CTSU S1007
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Status:
OPEN
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Key Eligibility:
ADJUVANT BREAST - Step 1 - hist confirmed dx of node pos(1-3 nodes) invasive br ca w/pos estrogen and/or progesterone receptor status,and neg HER-2; Step 2 - Recurrence score (RS) by Oncotype DX® must be less than or equal to 25
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File:
Download
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Description:
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Randomized Double-Blind Study of Doxepin Rinse versus Placebo in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy with or without Chemotherapy
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Disease Site:
Cancer Control
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Protocol Number:
N09C6
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Status:
OPEN
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Key Eligibility:
Malignancy undergoing course of RT; 1/3 of oral cavity mucosa must be included in RT fields
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File:
Download
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Description:
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A Phase II Study of L-BLP25 and Bevacizumab in Unresectable Stage IIIA and IIIB NonSquamous NSCLC after Definitive Chemoradiation
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Disease Site:
Lung
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Protocol Number:
E6508
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Status:
OPEN
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Key Eligibility:
NSCLC, Nonsquamous, IIIA and IIIB
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File:
Download
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Description:
No IMRT or 4D RT is allowed on this trial. The treating RT facility must have an approved 3D RT Benchmark on file with QARC.
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Randomized Phase III Trial of Lenalidomide Versus Observation Alone in Patients with Asymptomatic High-Risk Smoldering Multiple Myeloma
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Disease Site:
Hematology
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Protocol Number:
E3A06
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Status:
OPEN
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Key Eligibility:
Assymptomatic, high-risk, smoldering multiple myeloma
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File:
Download
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Description:
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A Randomized Phase II Study of Irinotecan and Cetuximab with or without the Anti-Angiogenic Antibody, Ramucirumab, in Advanced, K-ras Wild-type Colorectal Cancer Following Progression on Bevacizumab-Containing Chemotherapy
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Disease Site:
Gastrointestinal
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Protocol Number:
E7208
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Status:
OPEN
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Key Eligibility:
Met or adv CRC, KRAS-wild type, first line tx with Oxaliplatin-containing chemo and Avastin. PD within 90 days of last Avastin.
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File:
Download
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Description:
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Randomized Phase II Study of Paclitaxel With or Without the Anti-IGF-IR mAb Cixutumumab (IMC-A12) as Second Line Treatment for Patients With Metastatic Esophageal or GE Junction Cancer
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Disease Site:
Gastrointestinal
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Protocol Number:
E2208
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Status:
OPEN
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Key Eligibility:
Met Esophageal or GE Junction, AEG Type I and II.
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File:
Download
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Description:
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A Phase II Prospective Trial Correlating Progression Free Survival with CYP2D6 Activity in Patients with Metastatic Breast Cancer Treated with Single Agent Tamoxifen
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Disease Site:
Breast
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Protocol Number:
E3108
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Status:
OPEN
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Key Eligibility:
Stage III/Stage IV. No prior tx. No prior Tamoxifen
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File:
Download
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Description:
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A Phase III Trial of 6 versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer
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Disease Site:
Gastrointestinal
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Protocol Number:
C80702
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Status:
OPEN
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Key Eligibility:
Resected Stage III Colon
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File:
Download
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Description:
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Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC
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Disease Site:
Lung
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Protocol Number:
E5508
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Status:
OPEN
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Key Eligibility:
Advanced NSCLC, Non-Squamous
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File:
Download
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Description:
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Randomized, Phase III, Double-Blind Placebo-Controlled Trial of Sunitinib as Maintenance Therapy in Non-Progressing Patients following an Initial Four Cycles of Platinum-Based Combination Chemotherapy in Advanced, Stage IIIB/IV NSCLC
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Disease Site:
Lung
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Protocol Number:
C30607
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Status:
OPEN
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Key Eligibility:
NSCLC, Stage IIIB or IV First Line
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Description:
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A Randomized Phase III trial of Q-3-Wks Paclitaxel Plus Carbo vs Dose Dense Weekly Paclitaxel Plus Carbo with/without Concurrent and Consolidation Bevacizumab in the Trmt of Primary Stage III or IV Epithelial Ovarian, Peritoneal or Fallopian Tube Cancer
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Disease Site:
Gynecologic
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Protocol Number:
GOG 0262
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Status:
OPEN
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Key Eligibility:
Stage III or IV
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File:
Download
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Description:
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A Randomized Phase II Trial of Carboplatin, Paclitaxel, Bevacizumab, with or without Everolimus for Therapy of Metastatic Malignant Melanoma
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Disease Site:
Melanoma
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Protocol Number:
N0879
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Status:
OPEN
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Key Eligibility:
Metastatic Melanoma
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File:
Download
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Description:
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Randomized Phase III Trial of Paclitaxel Combined With Trastuzumab, Lapatinib, or Both as Neoadjuvant Treatment of HER2-Positive Primary Breast Cancer
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Disease Site:
Breast
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Protocol Number:
C40601
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Status:
OPEN
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Key Eligibility:
NeoAdjuvant HER2+ Breast
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File:
Download
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Description:
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A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
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Disease Site:
Breast
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Protocol Number:
B43
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Status:
OPEN
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Key Eligibility:
DCIS HER2 testing by NSABP
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File:
Download
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Description:
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An Intergroup Phase III Randomized Trial Comparing Melphalan, Prednisone and Thalidomide (MPT) Versus Melphalan, Prednisone and Lenalidomide (Revlimid™) (MPR) in Newly Diagnosed Multiple Myeloma Patients Who Are Not Candidates for High-Dose Therapy
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Disease Site:
Hematology
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Protocol Number:
E1A06
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Status:
OPEN
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Key Eligibility:
Newly Diagnosed Multiple Myeloma
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Description:
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Phase III Double Blind, Placebo Controlled Study of Donepezil in Irradiated Brain Tumor Patients
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Disease Site:
Cancer Control
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Protocol Number:
WFU91105
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Status:
OPEN
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Key Eligibility:
Aricept/Placebo for Pts Receiving Brain RT
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File:
Download
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Description:
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The Use of Glutathione (GSH) for Prevention of TAXOL/CBDCA Induced Peripheral Neuropathy: A Phase III Randomized, Double-Blind Placebo Controlled Study
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Disease Site:
Cancer Control
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Protocol Number:
N08CA
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Status:
OPEN
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Key Eligibility:
Peripheral Neuropathy, Taxol/Carboplatin
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File:
Download
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Description:
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A Phase III Randomized, Placebo-Controlled, Double-Blind Study of Intravenous Calcium/Magnesium in Two Different Versions to Prevent Oxaliplatin-Induced Sensory Neurotoxicity
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Disease Site:
Cancer Control
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Protocol Number:
N08CB
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Status:
OPEN
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Key Eligibility:
Ca/Mg++ or Placebo, Colorectal , FOLFOX
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File:
Download
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Description:
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Paclitaxel-Associated Acute Pain Syndrome Natural History Study
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Disease Site:
Cancer Control
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Protocol Number:
N08C1
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Status:
OPEN
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Key Eligibility:
Paclitaxel QOL
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File:
Download
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Description:
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A Prospective Observational Multi-Center Cohort Study to Assess the Incidence of Osteonecrosis of the Jaw (ONJ) in Cancer Patients with Bone Metastases Starting Zoledronic Acid Treatment
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Disease Site:
Cancer Control
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Protocol Number:
S0702
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Status:
OPEN
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Key Eligibility:
Pts Starting Zoledronic Acid / Osteonecrosis of the Jaw
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File:
Download
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Description:
OMAHA:Use Omaha IC
LINC: Use Lincoln IC
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Combination Cisplatin, Etoposide, and Sunitinib for untreated Extensive Stage Small Cell Lung Cancer: A Phase Ib/II Study
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Disease Site:
Lung
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Protocol Number:
C30504
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Status:
OPEN
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Key Eligibility:
SMALL CELL, Extensive Stage
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Description:
CLOSING TO ENROLLMENT 12/13/11
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Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer also Receiving Cisplatin and Etoposide
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Disease Site:
Lung
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Protocol Number:
C30610
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Status:
OPEN - Omaha sites only
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Key Eligibility:
SMALL CELL, Limited Stage
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Description:
OMAHA:Use Omaha IC
Not avail to Lincoln yet
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A Phase II Randomized Trial of Paclitaxel, Carboplatin, Bevacizumab with or without IMC-A12 in Patients with Advanced Non-Squamous, Non-Small Cell Lung Cancer
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Disease Site:
Lung
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Protocol Number:
E3508
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Status:
OPEN
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Key Eligibility:
Advanced NSCLC
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Description:
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A Phase III Randomized Trial of Adjuvant Chemotherapy with or without Bevacizumab for Patients with Completely Resected Stage IB (>/=+4CM)-IIIA Non-Small Cell Lung Cancer
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Disease Site:
Lung
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Protocol Number:
E1505
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Status:
OPEN
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Key Eligibility:
NSCLC, Stage IB-IIIA, Completely Resected
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Description:
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A Randomized Phase III Trial of Adjuvant Therapy in Early Stage Non-Small Cell Lung Cancer Evaluating the Potential Utility of a Genomic Prognostic Model to Identify Patients as Candidates for Adjuvant Chemotherapy
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Disease Site:
Lung
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Protocol Number:
C30506
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Status:
OPEN
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Key Eligibility:
Early Stage NSCLC
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Description:
CLOSING TO ENROLLMENT 11/30/11
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Randomized Phase II Trial of Pentostatin, Cyclophosphamide, and Rituximab With or Without Concurrent Avastin® for Previously Untreated B-Chronic Lymphocytic Leukemia (CLL)
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Disease Site:
Hematology
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Protocol Number:
RC0783
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Status:
OPEN
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Key Eligibility:
Untreated CLL
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Description:
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A Phase III Randomized Trial of Chemotherapy With or Without Bevacizumab in Patients with Recurrent or Metastatic Head and Neck Cancer
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Disease Site:
Head/Neck
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Protocol Number:
E1305
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Status:
OPEN
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Key Eligibility:
Recurrent or Metastatic H&N
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File:
Download
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Description:
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Randomized Phase III Trial Comparing the Frequency of Major Erythroid
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Disease Site:
Hematology
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Protocol Number:
E2905
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Status:
OPEN
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Key Eligibility:
Low- or Intermediate- MDS and Symptomatic Anemia
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Description:
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A Randomized Phase III Study of Standard Dosing versus Longer Dosing Interval of Zoledronic Acid in Metastatic Cancer
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Disease Site:
Genitourinary
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Protocol Number:
C70604
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Status:
OPEN
-
Key Eligibility:
Metastatic Prostate, Breast, MM
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File:
Download
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Description:
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A Randomized, Double-Blind, Placebo-Controlled Phase III Study of Early Versus Standard Zoledronic Acid to Prevent Skeletal Related Events in Men with Prostate Cancer Metastatic to Bone
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Disease Site:
Genitourinary
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Protocol Number:
C90202
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Status:
OPEN
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Key Eligibility:
Metastatic Prostate, Bone Mets
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File:
Download
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Description:
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A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer
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Disease Site:
Genitourinary
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Protocol Number:
RTOG 0815
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Status:
OPEN. RT credentialing required
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Key Eligibility:
Prostate, Intermediate-Risk, RT
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File:
Download
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Description:
Note: RT site credentialing pending – please check prior to screening/enrollment.
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A Phase III Trial of Irinitecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum
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Disease Site:
Gastrointestinal
-
Protocol Number:
C80405
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Status:
OPEN
-
Key Eligibility:
Colon or Rectum, Untreated Metastatic
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File:
Download
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Description:
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Phase II Trial of Cetuximab Plus Cisplatin, 5-Fluorouracil, and Radiation in Immunocompetent Patients with Anal Carcinoma
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Disease Site:
Gastrointestinal
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Protocol Number:
E3205
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Status:
OPEN
-
Key Eligibility:
Anal
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File:
Download
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Description:
-
A Randomized Phase II Study to Determine the Effect of 2 Different Doses of AVE0005 (VEGF Trap) in Patients with Metastatic Renal Cell Carcinoma
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Disease Site:
Genitourinary
-
Protocol Number:
E4805
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Status:
OPEN
-
Key Eligibility:
Renal Cell, SECOND LINE, Prior Sutent/Nexavar
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File:
Download
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Description:
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A Double Blind Phase II Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients with Advanced Transitional Cell Carcinoma
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Disease Site:
Genitourinary
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Protocol Number:
C90601
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Status:
OPEN
-
Key Eligibility:
Advanced Bladder, Transitional Cell
-
File:
Download
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Description:
-
Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer
-
Disease Site:
Genitourinary
-
Protocol Number:
C90203
-
Status:
OPEN
-
Key Eligibility:
Prostate, NeoAdjuvant, High-Risk, Clinically Localized
-
File:
Download
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Description:
-
Phase II Study of Treatment Selection Based Upon Tumor Thymidylate Synthase Expression in Previously Untreated Patients with Metastatic Colorectal Cancer
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Disease Site:
Gastrointestinal
-
Protocol Number:
E4203
-
Status:
OPEN
-
Key Eligibility:
Metastatic Colorectal Previously Untreated
-
File:
Download
-
Description:
-
Polyp Prevention Trial in Patients with Resected Colon Cancer
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Disease Site:
Gastrointestinal
-
Protocol Number:
P5
-
Status:
OPEN
-
Key Eligibility:
Stage I and II colon
-
File:
Download
-
Description:
-
A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients With Esophageal Cancer Who Are Treated Without Surgery
-
Disease Site:
Gastrointestinal
-
Protocol Number:
R0436
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Status:
SUSPENDED - RT credentialing pending
-
Key Eligibility:
Esophageal
-
File:
Download
-
Description:
Note: RT site credentialing pending – please check prior to screening/enrollment.
-
Phase III Prospective Randomized Comparison of Depot Octreotide Plus Interferon Alpha Versus Depot Octreotide Plus Bevacizumab (NSC #704865) in Advanced, Poor Prognosis Carcinoid Patients
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Disease Site:
Carcinoid
-
Protocol Number:
CTSU S0518
-
Status:
OPEN
-
Key Eligibility:
Advanced Carcinoid, Poor Prognosis
-
File:
Download
-
Description:
-
Phase II Trial of Brostallicin and Cisplatin in Patients with Metastatic Triple Negative Breast Cancer
-
Disease Site:
Breast
-
Protocol Number:
N0937
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Status:
Temp Closed
-
Key Eligibility:
Metastatic Triple Negative
-
File:
Download
-
Description:
Temp closure for interim analysis effective 2/11/2011
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A Randomized Phase III Study of Standard Dosing versus Longer Dosing Interval of Zoledronic Acid in Metastatic Cancer
-
Disease Site:
Breast
-
Protocol Number:
C70604
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Status:
OPEN
-
Key Eligibility:
Metastatic Breast, No Prior Zometa
-
File:
Download
-
Description:
-
Endocrine Therapy with or without anti-VEGF Therapy: A Randomized, Phase III Trial of Endocrine Therapy Alone or Endocrine Therapy Plus Bevacizumab (NSC 704865; IND 7921) For Women with Hormone Receptor-Positive Advanced Breast Cancer
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Disease Site:
Breast
-
Protocol Number:
C40503
-
Status:
OPEN
-
Key Eligibility:
Metastatic ER/PR+ FIRST LINE
-
File:
Download
-
Description:
CLOSING TO ENROLLMENT EFFECTIVE 11/30/11
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A Randomized, Phase III Trial of Weekly Paclitaxel Compared to Weekly Nanoparticle Albumin Bound NAB-Paclitaxel or Ixabepilone Combined with Bevacizumab as First-Line Therapy for Locally Recurrent or Metastatic Breast Cancer
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Disease Site:
Breast
-
Protocol Number:
C40502
-
Status:
OPEN
-
Key Eligibility:
Recurrent or Metastatic Breast FIRST LINE
-
File:
Download
-
Description:
-
Phase III Trial of continuous Schedule AC + G vs. Q 2 Week Schedule AC, Followed by Paclitaxel Given either Every 2 Weeks or Weekly for 12 Weeks as Post-Operative Adjuvant Therapy in Node-Positive or High Risk Node Negative Breast Cancer
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Disease Site:
Breast
-
Protocol Number:
S0221
-
Status:
OPEN
-
Key Eligibility:
Adjuvant Node Positive or High Risk Node Negative
-
File:
Download
-
Description:
-
A Phase I/II Trial of Sorafenib and CCI-779 in Patients with Recurrent Glioblastoma
-
Disease Site:
Brain
-
Protocol Number:
N0572
-
Status:
OPEN. Arm B temp closed
-
Key Eligibility:
Recurrent Glioblastoma
-
File:
Download
-
Description:
Note: RT site credentialing pending - please check prior to screening / enrollment.
Arm B IS CLOSED. Please note: Study 2, Group 2(Arm C, patients undergoing surgery) and Group 3 (Arm D, patients with prior anti-VEGF treatment and not undergoing surgery) remain open for accrual.
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Phase I/II Evaluation of Everolimus (RAD001), Radiation and Temozolomide (TMZ) Followed by Adjuvant Temozolomide and Everolimus in Newly Diagnosed Glioblastoma
-
Disease Site:
Brain
-
Protocol Number:
N057K
-
Status:
TEmp Closed eff 1/17/11 - RT credentialing required for IMRT
-
Key Eligibility:
Newly Diagnosed Glioblastoma
-
File:
Download
-
Description:
Note: RT facility credentialing required for IMRT
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Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients with One to Three Cerebral Metastases
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Disease Site:
Brain
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Protocol Number:
N0574
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Status:
OPEN
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Key Eligibility:
1 to 3 cerebral metastases
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File:
Download
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Description:
Note: SRS approval at Immanuel location only
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Phase III Intergroup Study of Radiotherapy versus Temozolomide alone versus Radiotherapy with Concomitant and Adjuvant Temozolomide for Patients with 1p/19q Codeleted Anaplastic Glioma
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Disease Site:
Brain
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Protocol Number:
N0577
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Status:
OPEN
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Key Eligibility:
1p/19q Co-deleted Anaplastic Glioma
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File:
Download
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Description:
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Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas
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Disease Site:
Brain
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Protocol Number:
E3F05
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Status:
OPEN
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Key Eligibility:
Symptomatic Gliomas
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File:
Download
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Description: